In addition to activities at the European level, the coalition is also focusing on national-level initiatives where access decisions are made. In Italy and Spain, the coalition is collaborating with national policymakers to overcome barriers in patient access. Aligned with the Europe’s Beating Cancer Plan and Cancer Mission’s call to “leave no stone unturned to take action against cancer”, ECGP considers CGP adoption essential for advancing personalised medicine.

Overview

The Italian chapter addresses critical challenges in accessing comprehensive genomic profiling (CGP) across the country. Despite its strong potential for enabling precision cancer care, CGP is not currently covered within the national healthcare system (SSN – Sistema Sanitaro Nazionale).

As a result, significant regional disparities persist, with some regions benefiting from advanced infrastructure and networks, while others continue to face substantial gaps in access to CGP testing.

ECGP Activities

The ECGP Italian chapter has positioned itself as a key convener of national stakeholders, bringing together multidisplinary expertise to advance CGP access and policy prioritisation. The iniative is specifically focused on:

• Supporting the inclusion of CGP within the Livelli Essenziali di Assentenza (LEA), the nationally mandated package of reimbursed healthcare services under the Italian SSN
• Promoting the standardisation of laboratory practices
• Raising awareness among key stakeholders and decision-makers

Key Milestones

17 December 2024: Launch of multidisplinary expert board

May 2025: Strategic document develoment (including LEA updates)

3 July 2025: Institutional event with representatives of the Italian Chamber of Deputies and Senate

Overview

The Spanish healthcare system (SNS – Sistema Nacional de Salud) is highly decentralised across 17 autonomous regions, allowing tailored policy implementation. However, this leads to unequal access to CGP and genomic testing, with significant disparities between regions.

ECGP Activities

The ECGP Spanish chapter focuses on regional collaboration and knowledge exchange, working directly with local decision-makers. Key actions include:

• Partnerships with Catalonia, Valencia and Aragon
• Organisation of technical discussion between regional authorities and industry
• Facilitation of best practice sharing across
• Support for implementation strategies tailored to regional contexts

Key Milestones

14 July 2025: Regional meeting in Valencia

17 July 2025: Regional meeting in Catalonia

21 October 2025: Regional meeting in Aragon

Overview

In France, CGP is not included in the reimbursement codes of the French National Authority for Health (HAS – Haute Autorité de Santé), limiting its integration into routine clinical practice.

Despite strong expertise in oncology and genomics, access to CGP remains limited and fragmented, with key challenges related to funding pathways, prioritisation, and national coordination.

ECGP Activities

The ECGP French chapter is working to bring CGP higher on the national policy agenda by fostering collaboration among key stakeholders. Key actions include:

• Convening a national group of experts and stakeholders to support CGP adoption
• Raising awareness among policymakers on the clinical and economic value of CGP
• Supporting discussions on reimbursement pathways and integration into national systems
• Facilitating alignment between clinicals, policymakers, and industry representatives